Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Vitamin E (alpha-tocopherol) is an antioxidant vitamin that has been studied for its role in supporting male reproductive health, including the function of the testes. Scientific evidence suggests that Vitamin E helps protect testicular tissue from oxidative damage, which is important because the testes are particularly susceptible to oxidative stress due to high rates of cell division and metabolic activity involved in spermatogenesis. Animal studies have demonstrated that Vitamin E deficiency leads to testicular degeneration, impaired spermatogenesis, and reduced fertility. In humans, some clinical studies have found that Vitamin E supplementation can improve semen quality and motility, particularly in men with infertility linked to oxidative stress. For example, a randomized controlled trial (Keskes-Ammar et al., 2003) showed that a combination of Vitamin E and selenium improved sperm motility and decreased lipid peroxidation in infertile men. However, while these findings are promising, the evidence is not entirely consistent, and large-scale, well-controlled human studies are still lacking. Overall, Vitamin E’s use to support the testes is primarily justified by its biological function as an antioxidant and some supportive clinical data, but the evidence base is moderate rather than conclusive.

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