Rosavins are a group of compounds found primarily in the root of Rhodiola rosea, a traditional adaptogenic herb. The use of Rosavins to support the sympathetic nervous system is grounded in both traditional practice and emerging scientific research. The sympathetic nervous system is responsible for the body's "fight or flight" response, and adaptogens like Rhodiola rosea are believed to help modulate stress responses and support resilience to physical and mental stressors.

Several clinical and preclinical studies have investigated Rhodiola rosea extracts standardized to Rosavins for their potential to reduce fatigue, improve mental performance, and support stress adaptation. Some double-blind, placebo-controlled trials have shown that Rhodiola supplementation can reduce stress-induced fatigue and improve cognitive function under stress, suggesting a modulatory effect on the stress response, which is mediated by the sympathetic nervous system. Proposed mechanisms include modulation of cortisol levels, support of neurotransmitter balance, and influence on stress-responsive signaling pathways.

However, while the evidence is promising, most studies use standardized extracts containing both Rosavins and Salidroside, making it difficult to attribute effects solely to Rosavins. Larger, high-quality human studies are still needed to confirm efficacy and clarify mechanisms. Thus, the scientific evidence supporting the use of Rosavins for sympathetic nervous system support is moderate (rated 3/5).