Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Rosarin is a phenylpropanoid glycoside found in the plant Rhodiola rosea, commonly known as "golden root" or "arctic root." Rhodiola rosea has a long history in traditional medicine, particularly in Russia, Scandinavia, and parts of Asia, where it was used to increase physical endurance, work productivity, longevity, and resistance to high-altitude sickness. However, the justification for its use to support the sympathetic nervous system comes primarily from scientific research into its adaptogenic properties.

Several studies have identified rosavin, salidroside, and rosarin as the main active compounds in Rhodiola rosea. The adaptogenic effects are thought to be mediated by modulation of neurotransmitters such as norepinephrine, serotonin, and dopamine, which are closely tied to the sympathetic nervous system’s "fight or flight" response. Preclinical and some clinical evidence suggest that extracts standardised for rosarin and related compounds may help mitigate fatigue, enhance stress resistance, and support cognitive function under stress—all functions related to sympathetic nervous system activation.

However, while the overall evidence base for Rhodiola rosea is moderate, most studies use whole plant extracts, not isolated rosarin. Therefore, while there is scientific justification for the use of rosarin-containing extracts to support the sympathetic nervous system, the direct evidence for isolated rosarin is more limited. The rating of 3 reflects moderate scientific support, primarily extrapolated from studies on Rhodiola rosea extracts.

More about Rosarin
More about Sympathetic Nervous System

Other ingredients that support Sympathetic Nervous System

Other body systems supported by Rosarin

Products containing Rosarin