Jiaogulan (Gynostemma pentaphyllum) is a climbing vine traditionally used in Chinese and Southeast Asian herbal medicine. It is often referred to as "Southern Ginseng" due to its adaptogenic properties, meaning it is believed to help the body adapt to stress. In traditional medicine, jiaogulan is used to enhance energy, stamina, and overall vitality, which indirectly suggests support for the Sympathetic Nervous System (SNS)—the branch of the autonomic nervous system responsible for the "fight or flight" response.

While traditional use supports jiaogulan’s role in boosting energy and resilience, direct scientific evidence specifically linking jiaogulan to modulation or support of the SNS is limited. Most scientific studies focus on its antioxidant, anti-inflammatory, and potential cardiovascular effects, as well as its ability to modulate metabolic factors. Some animal studies suggest adaptogenic effects, which may involve indirect influence on SNS activity by helping the body manage stress responses, but these effects are not well-established in humans.

In summary, the use of jiaogulan to support the Sympathetic Nervous System is primarily rooted in traditional medicine, with a low to moderate level of supporting evidence (rated 2/5) due to a lack of direct scientific validation for this specific application.