Evidence supporting the use of: Lobelia
For the body system: Sweat Glands

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Lobelia (Lobelia inflata), also known as Indian tobacco, has a long history of use in traditional herbal medicine, particularly by Native American groups and in 19th-century Western herbalism. Traditionally, lobelia was considered a "stimulating expectorant" and used to promote sweating (diaphoresis), which was thought to help break fevers and eliminate toxins. Its use as a diaphoretic is documented in historical texts, where it was included in various formulas aimed at supporting the body's natural cooling and detoxification processes via sweat glands. However, the mechanism was based on humoral theories and early herbalist concepts rather than scientific understanding.

Modern scientific validation for lobelia's effects specifically on the sweat glands is lacking. Most current research on lobelia focuses on its alkaloids, particularly lobeline, which affects the respiratory system and acts as a nicotinic agonist. There is very little to no direct research supporting its efficacy in stimulating sweat production or supporting sweat gland function. Thus, while its use for this purpose is supported by tradition, there is insufficient modern evidence to confirm its effectiveness or safety for specifically supporting the sweat glands.

Due to potential toxicity, especially at higher doses, lobelia should be used with caution and under the guidance of a qualified practitioner.

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