Evidence supporting the use of: Calotropis gigantea
For the health condition: Sunburn

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Calotropis gigantea, commonly known as crown flower or giant milkweed, has a long history of use in traditional medicine systems such as Ayurveda and folk medicine across South and Southeast Asia. Traditionally, its leaves, latex, and extracts have been applied topically to treat skin ailments, including wounds, eczema, and burns, which may encompass sunburns. The rationale behind such usage is often attributed to the plant's purported anti-inflammatory, analgesic, and soothing properties. However, documentation specifically targeting sunburn is limited, and most references are general to "burns" or skin irritations. Scientific studies on Calotropis gigantea primarily highlight its antimicrobial, anti-inflammatory, and wound-healing properties in vitro and in animal models, but there is little direct scientific research examining its effectiveness for sunburn specifically. The plant contains bioactive compounds such as flavonoids, triterpenoids, and cardenolides, which may contribute to anti-inflammatory effects, but clinical trials validating its safety and efficacy for sunburn in humans are lacking. Additionally, the plant's latex can be irritating or toxic to skin and mucous membranes, raising safety concerns for topical use. In summary, while Calotropis gigantea is used in traditional medicine for various skin conditions, scientific evidence for its use in sunburn is minimal, and caution is warranted due to potential toxicity.

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