Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Hydroxycitric acid (HCA), most commonly derived from the rind of the Garcinia cambogia fruit, has been promoted as a supplement to reduce appetite and support weight loss, which includes claims about reducing sugar cravings. The scientific rationale is that HCA inhibits the enzyme ATP-citrate lyase, which plays a role in the conversion of carbohydrates into fat, and may also increase serotonin levels in the brain, potentially leading to reduced appetite and fewer cravings for carbohydrates and sugar.

Several small clinical studies and animal experiments have investigated HCA’s effects on appetite and sugar cravings. Some studies suggest a modest reduction in appetite, with a few participants reporting decreased cravings for sugary foods. However, larger and more rigorous clinical trials have often found little to no significant effect of HCA supplementation compared to placebo in terms of reducing appetite or sugar cravings specifically. A 2011 meta-analysis (Onakpoya et al., Journal of Obesity) concluded that while there is some evidence of short-term weight loss, the effects are small and clinical relevance is questionable.

Overall, while there is a plausible biological mechanism and some preliminary evidence, the clinical support for HCA specifically reducing sugar cravings is weak and inconsistent. Therefore, its use for sugar craving management is based on limited scientific evidence and should be considered with caution.

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