Evidence supporting the use of: Vitamin D (ergocalciferol)
For the body system: Structural System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin D, including its form ergocalciferol (vitamin D2), is scientifically validated as essential for the maintenance and support of the structural system, primarily the bones and skeletal framework. Vitamin D facilitates the intestinal absorption of calcium and phosphate, both of which are critical minerals for bone mineralization and maintenance. Deficiency of vitamin D leads to conditions such as rickets in children (characterized by bone deformities) and osteomalacia in adults (softening of the bones), highlighting its crucial role in skeletal health. Numerous randomized controlled trials, meta-analyses, and clinical guidelines support the use of vitamin D supplementation (including ergocalciferol) in the prevention and treatment of osteoporosis and other metabolic bone diseases, especially in populations at risk for deficiency. The Institute of Medicine and major endocrinology societies recommend vitamin D for bone health. Furthermore, ergocalciferol is an approved pharmacological option for the treatment of vitamin D deficiency and associated bone disorders. In summary, the use of vitamin D (ergocalciferol) to support the structural system is strongly justified by robust scientific evidence.

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