Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Strontium, particularly in the form of strontium ranelate, has scientific validation for its use in supporting the structural system, specifically bone health. Strontium is chemically similar to calcium and can be incorporated into bone tissue. Clinical studies, especially in Europe, have shown that strontium ranelate can reduce the risk of vertebral and non-vertebral fractures in postmenopausal women with osteoporosis. The main mechanism is believed to be a dual action: it both increases bone formation by osteoblasts and decreases bone resorption by osteoclasts. Meta-analyses and randomized controlled trials have reported improvements in bone mineral density and reduced fracture rates versus placebo.

However, the approval of strontium ranelate for osteoporosis treatment is limited to some countries. In the United States, it is not approved for this use, partly due to concerns about cardiovascular risks associated with its use. Dietary forms of strontium (like strontium citrate) are available as supplements, but there is less robust clinical evidence supporting these forms for bone health. Most of the high-quality evidence is linked to the prescription form, strontium ranelate. Overall, strontium’s use to support the structural system is scientifically validated, particularly for osteoporosis, but its safety profile warrants careful consideration.

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