Silicon is a trace mineral that plays a role in the maintenance of the structural system, particularly connective tissues such as bone, cartilage, skin, hair, and nails. Scientific evidence indicates that silicon is involved in the synthesis and stabilization of collagen and glycosaminoglycans, which are key components of the extracellular matrix in these tissues. Animal studies have demonstrated that silicon deficiency can lead to skeletal abnormalities, impaired bone growth, and defective joint cartilage. In humans, observational studies have associated higher dietary silicon intake with increased bone mineral density, particularly in premenopausal women, though causality has not been definitively established. Silicon may enhance the deposition of calcium and other minerals in bone, contributing to bone strength and resilience.

However, while there is supportive data from animal and epidemiological studies, large-scale, controlled human clinical trials are limited. The mechanisms by which silicon supports bone health are still under investigation, and its essentiality in human nutrition has not been universally recognized. Nevertheless, the existing body of evidence provides a plausible scientific rationale for the inclusion of silicon in supplements aimed at supporting the structural system, especially for bone and connective tissue health. Overall, silicon’s use is justified by scientific evidence, though the evidence is moderate rather than strong.