Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Semecarpus anacardium, commonly known as the marking nut, has a rich history of use in traditional Ayurvedic medicine. It is traditionally classified as a "Rasayana" herb, believed to rejuvenate the body and mind, and has been used in Ayurvedic formulations addressing a variety of physical and psychological ailments, including stress and anxiety. Historical texts and traditional practitioners have recommended its use for promoting vitality and balancing the body's systems, which indirectly supports resilience to stress. However, direct clinical evidence evaluating the anti-stress or adaptogenic effects of Semecarpus anacardium in humans is limited. Some preclinical studies in animals suggest that extracts of this plant may have anti-stress or anxiolytic effects, potentially through antioxidant mechanisms or modulation of neurotransmitters, but these studies are preliminary and not sufficient for establishing scientific validation. Overall, while its use for stress is rooted in traditional systems of medicine, high-quality human studies are lacking, so the strength of evidence supporting its use for stress remains low.

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