Evidence supporting the use of: Schisandrins
For the health condition: Stress

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Schisandrins are bioactive compounds found in Schisandra chinensis, a plant widely used in Traditional Chinese Medicine (TCM). Historically, Schisandra berries have been classified as an "adaptogen," a term for substances believed to help the body resist physical, chemical, or biological stressors. In TCM, Schisandra is thought to "calm the spirit," improve mental function, and enhance resilience to stress, and it has been included in various formulations intended to support stress resistance and vitality.

Scientific research on Schisandrins and stress is limited but emerging. Some preclinical studies (mainly in animals and cell models) indicate that Schisandra extracts and Schisandrins may modulate the hypothalamic-pituitary-adrenal (HPA) axis, reduce stress-induced biochemical changes, and improve markers of cognitive and physical performance under stress. However, robust human clinical trials confirming these effects are lacking. Therefore, while the traditional use is strong and there is some preliminary scientific rationale, the current evidence base remains modest, and most claims are not yet validated by rigorous clinical research. As such, the use of Schisandrins for stress is primarily justified by tradition, supported by limited (but promising) scientific investigations.

More about Schisandrins
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Other ingredients used for Stress

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7-Keto-DHEA
acetyl l-carnitine
alpha-pinene
arjun tree
ashwagandha
asparagus
astragalus
waterhyssop
benegut perilla (proprietary)
bergamot
bifidobacterium bifidum
bifidobacterium lactis
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bupleurum falcatum
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caterpillar mushroom
chaga mushroom
chamomile
cordyceps
curcumin
damiana
DHA (docosahexaeonic acid)
dong quai root
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
GABA (gamma aminobutyric acid)
gardenia
gotu kola
green tea
guayusa
heartwood
hibiscus
hops
jujube
kava root
kudzu
l-ornithine
l-taurine
l-theanine
l-tryptophan
l-tyrosine
lactium casein decapeptide
lactobacillus brevis
lactobacillus casei
lactobacillus helveticus
lactiplantibacillus plantarum
lavender
lentinula edodes mycelia
lion's mane
liquid liver fractions
maca
magnesium
magnolia
matcha
melatonin
mint
motherwort
muira puama
Acetyl-L-Tyrosine
oat
passionflower
peppermint oil
perilla
phosphatidylserine
phospholipids
pine bark
polygala root
pregnenolone
pyrroloquinoline disodium salt
quail egg
relora® (proprietary)
rhodiola
rose oil
saffron
sceletium
black ginger
skullcap
spearmint leaf
spinach
valerian root
velvet bean
vitamin B12
vitamin B6
mulberry
whole adrenal glandular
zinc
sarsaparilla
suma
jiaogulan
catnip
cardamom
anise
fumaria parviflora
bee pollen
lingzhi
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ashitaba
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Antler
Agastache
Agrimony
Apigenin
Antrodia camphorata
Arginine aspartate
Albizia
Anserina
Agmatine
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Alpha lactalbumin
Algal protein
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Baikal Skullcap
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Baccosides
Bacopin
Baicalein
Basidiomycota
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banana
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Codonopsis
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Centella asiatica
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jasmine
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Products containing Schisandrins

We currently have no products on Caring Sunshine that contain this ingredient.