Poris Mushroom, also known as Poria cocos or Fu Ling in traditional Chinese medicine (TCM), has a long history of use for various health concerns, including calming the mind and alleviating symptoms associated with stress, such as anxiety and insomnia. In TCM, Poris Mushroom is believed to "strengthen the spleen," promote urination, and "calm the spirit" (anxiolytic and sedative effects), making it a popular ingredient in formulas aimed at treating stress-related disorders. Its traditional use is well documented in classical texts such as the Shennong Bencao Jing and it continues to feature prominently in contemporary Chinese herbal practice.

Scientific validation for the use of Poris Mushroom specifically for stress is limited. Some preclinical studies have investigated its potential neuroprotective and anti-anxiety effects, but robust human clinical trials are lacking. Most of the supportive evidence remains at the level of traditional usage and animal studies, with few direct studies on stress in humans. Therefore, while Poris Mushroom is widely used in traditional medicine for stress and related symptoms, the scientific evidence to support this specific use is currently considered preliminary and not conclusive.