Evidence supporting the use of: Ginseng, Panax
For the health condition: Stress

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Panax ginseng has a long history of use in traditional medicine systems, particularly in East Asia, for enhancing resilience to stress and boosting overall vitality. Modern scientific research has begun to investigate these traditional claims, focusing on ginseng’s potential adaptogenic properties—substances thought to help the body resist physical, chemical, or biological stressors. Several randomized, placebo-controlled clinical trials have explored Panax ginseng’s effects on stress and related symptoms. Some studies have reported modest improvements in subjective measures of mental fatigue, perceived stress, and quality of life in healthy adults or those exposed to stressors. The proposed mechanisms involve modulation of the hypothalamic-pituitary-adrenal (HPA) axis, regulation of cortisol levels, and antioxidant effects of ginsenosides, the main active compounds in Panax ginseng. However, the clinical evidence is mixed, with some trials failing to show significant benefits, and methodological limitations (such as small sample sizes and inconsistent outcome measures) are common. Systematic reviews generally conclude that while Panax ginseng appears safe and shows potential for reducing stress and improving well-being, the quality and consistency of evidence are insufficient for firm conclusions. Therefore, its use for stress is supported by a combination of traditional use and preliminary scientific validation, but more rigorous research is needed to establish efficacy and optimal dosing.

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acetyl l-carnitine
alpha-pinene
arjun tree
ashwagandha
asparagus
astragalus
waterhyssop
benegut perilla (proprietary)
bergamot
bifidobacterium bifidum
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bupleurum falcatum
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caterpillar mushroom
chaga mushroom
chamomile
cordyceps
curcumin
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DHA (docosahexaeonic acid)
dong quai root
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
GABA (gamma aminobutyric acid)
gardenia
gotu kola
green tea
guayusa
heartwood
hibiscus
hops
jujube
kava root
kudzu
l-ornithine
l-taurine
l-theanine
l-tryptophan
l-tyrosine
lactium casein decapeptide
lactobacillus brevis
lactobacillus casei
lactobacillus helveticus
lactiplantibacillus plantarum
lavender
lentinula edodes mycelia
lion's mane
liquid liver fractions
maca
magnesium
magnolia
matcha
melatonin
mint
motherwort
muira puama
Acetyl-L-Tyrosine
oat
passionflower
peppermint oil
perilla
phosphatidylserine
phospholipids
pine bark
polygala root
pregnenolone
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quail egg
relora® (proprietary)
rhodiola
rose oil
saffron
sceletium
black ginger
skullcap
spearmint leaf
spinach
valerian root
velvet bean
vitamin B12
vitamin B6
mulberry
whole adrenal glandular
zinc
sarsaparilla
suma
jiaogulan
catnip
cardamom
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fumaria parviflora
bee pollen
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jasmine
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Products containing Ginseng, Panax

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