Evidence supporting the use of: Curcumin
For the health condition: Stress
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Curcumin, the primary bioactive compound found in turmeric (Curcuma longa), has gained interest for its potential role in supporting stress management. The justification for its use is primarily based on recent scientific research, although traditional systems like Ayurveda have used turmeric for general wellness and inflammation rather than specifically for stress.
Scientific studies suggest that curcumin may exert anti-stress effects primarily through its anti-inflammatory and antioxidant properties. Chronic psychological stress is associated with increased oxidative stress and inflammation, both of which are known contributors to mood disorders. Preclinical (animal) studies have demonstrated that curcumin can modulate neurotransmitters such as serotonin and dopamine, and may reduce markers of inflammation and oxidative stress in the brain. Several small human clinical trials have examined curcumin supplementation in individuals experiencing depressive symptoms, stress, or anxiety, showing modest improvements in mood and perceived stress compared to placebo.
However, the overall quality of evidence is moderate at best. Most clinical research to date involves small sample sizes, short durations, and varying curcumin formulations with limited bioavailability. While preliminary results are promising, especially for mood and stress-related symptoms, larger and more rigorous human studies are needed to confirm these effects and determine optimal dosing. Thus, curcumin is scientifically investigated for stress, but the strength of the evidence is currently rated as 2 out of 5.
Other ingredients used for Stress
5-Hydroxytryptophan (5-HTP)7-Keto-DHEA
acetyl l-carnitine
alpha-pinene
arjun tree
ashwagandha
asparagus
astragalus
waterhyssop
benegut perilla (proprietary)
bergamot
bifidobacterium bifidum
bifidobacterium lactis
bifidobacterium longum
sesame
black tea
bonito peptide
bupleurum falcatum
California poppy
caterpillar mushroom
chaga mushroom
chamomile
cordyceps
curcumin
damiana
DHA (docosahexaeonic acid)
dong quai root
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
GABA (gamma aminobutyric acid)
gardenia
gotu kola
green tea
guayusa
heartwood
hibiscus
hops
jujube
kava root
kudzu
l-ornithine
l-taurine
l-theanine
l-tryptophan
l-tyrosine
lactium casein decapeptide
lactobacillus brevis
lactobacillus casei
lactobacillus helveticus
lactiplantibacillus plantarum
lavender
lentinula edodes mycelia
lion's mane
liquid liver fractions
maca
magnesium
magnolia
matcha
melatonin
mint
motherwort
muira puama
Acetyl-L-Tyrosine
oat
passionflower
peppermint oil
perilla
phosphatidylserine
phospholipids
pine bark
polygala root
pregnenolone
pyrroloquinoline disodium salt
quail egg
relora® (proprietary)
rhodiola
rose oil
saffron
sceletium
black ginger
skullcap
spearmint leaf
spinach
valerian root
velvet bean
vitamin B12
vitamin B6
mulberry
whole adrenal glandular
zinc
sarsaparilla
suma
jiaogulan
catnip
cardamom
anise
fumaria parviflora
bee pollen
lingzhi
kanna
silk tree
oriental arborvitae
anemarrhena asphodeloides
St. John's Wort
yerba mate
noni
wood betony
biota seed
goji berry
cocoa
AMP-activated protein kinase (AMPK)
ashitaba
7,8-Dihydroxyflavone
Aralia
Arjuna
akebia
Antler
Agastache
Agrimony
Apigenin
Antrodia camphorata
Arginine aspartate
Albizia
Anserina
Agmatine
Agarwood
Alpha lactalbumin
Algal protein
Betony
Baikal Skullcap
Black spruce
Baccosides
Bacopin
Baicalein
Basidiomycota
Banyan
Brahmi
Bacopa
Buddha's Hand
Borage
banana
Bifidobacteria
Bupleurum
bacoside
Baicalin
Bird's nest
Centella triterpenes
Common Monkey Flower
Clary sage
Chinese Mountain Ant
Codonopsis
Coriander
Clerodendrum phlomidis
Chinese Fleeceflower
Chuchuhuasi
Cymbopogon Martini
Calea zacatechichi
Centella asiatica
Coca
Chocolate
Capitate Valerian
Corktree
Catuaba
C-Phycocyanin
cypress
Cowslip
Calamus
Cherimoya
Convolvulus prostratus
Corydalis
Convolvulus Pluricaulis
Celastrus
Canscora
Dismutase
Dodeca-2E, 4E-Dienoic Acid Isobutylamide
Dibenzo-alpha pyrones
Devil's Club
Date
Dodeca-2E, 4E, 8Z, 10Z/Etetraenoic Acid Isobutylamide
Eplotab
Erythrina
Emblicanin
Goldthread
Glycine
jasmine
Lotus
Mistletoe
Mimosa
Orchid
Poppy
Pistachio
Rose
Spikenard
yohimbine
Other health conditions supported by curcumin
AbscessesAcne
Adenitis
Aging (prevention)
Allergies (respiratory)
Alzheimer's Disease
Anal Fistula or Fissure
Angina
Antibiotics (alternatives to)
Anxiety
Anxiety Disorders
Arteriosclerosis
Arthritis
Asthma
Athletic and Exercise Aids
Autism
Autoimmune Disorders
Backache
Belching
Benign Prostate Hyperplasia
Bites and Stings
Bleeding (external)
Blood Clots (prevention of)
Body Building
Boils
Breast Lumps
Broken Bones
Bronchitis
Bruises (healing)
Bruises (prevention)
Burns and Scalds
Bursitis
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Canker Sores
Carbuncles
Cardiovascular Disease
Cartilage Damage
Celiac Disease
Cervical Dysplasia
Chemical Poisoning
Chemotherapy (reducing side effects)
Cholesterol (high)
Chronic Obstructive Pulmonary Disorder
Circulation (poor)
Cirrhosis of the Liver
Colitis
Crohn's Disease
Depression
Diabetes
Dyspepsia
Eczema
Endometriosis
Fatty Liver Disease
Fibromyalgia Syndrome
Fibrosis
Indigestion
Infection (bacterial)
Infection (viral)
Inflammation
Inflammatory Bowel Disorders
Irritable Bowel Syndrome
Liver Detoxification
Memory and Brain Function
Metabolic Syndrome
Migraine
Osteoporosis
Pain (general remedies for)
Pancreatitis
Pap Smear (abnormal)
Parkinson's Disease
Peripheral Neuropathy
Psoriasis
Rheumatoid Arthritis
Spinal Disks
Stress
Ulcers
Wounds and Sores