Chinese Blackberry, also known as Morus alba or white mulberry, has a long history of use in Traditional Chinese Medicine (TCM). In TCM, both the fruit and leaves are believed to nourish the yin, tonify the blood, and calm the spirit, which are associated with alleviating symptoms of stress, anxiety, and restlessness. The fruit is sometimes included in herbal formulas intended to support mental well-being and combat fatigue or nervous tension. However, these uses are primarily based on traditional theories and empirical observations rather than modern scientific validation.

To date, there is limited scientific research specifically examining the effects of Chinese Blackberry on stress in humans. Some laboratory studies have explored the antioxidant and neuroprotective properties of Morus alba extracts, which could theoretically contribute to stress reduction, but these findings are preliminary and do not directly translate to clinical efficacy for stress management. No high-quality clinical trials have established a clear benefit of Chinese Blackberry for stress. Thus, its use for this purpose is largely grounded in traditional practice rather than robust scientific evidence.