Evidence supporting the use of: Bifidobacteria
For the health condition: Stress
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Bifidobacteria is a genus of probiotic bacteria commonly found in the human gut, and its use in supporting stress management is primarily justified by emerging scientific evidence. Several preclinical and clinical studies suggest that Bifidobacteria may influence the gut-brain axis, a bidirectional communication system between the gastrointestinal tract and the central nervous system. For example, a 2017 randomized controlled trial published in Translational Psychiatry found that supplementation with Bifidobacterium longum 1714 reduced perceived stress and improved memory in healthy volunteers. Other studies have demonstrated that certain Bifidobacteria strains can lower cortisol levels and modulate inflammatory markers associated with stress response.
The proposed mechanisms include modulation of gut microbiota composition, reduction of systemic inflammation, and direct effects on neurotransmitter production (such as serotonin and GABA). However, while animal models show more robust effects, human evidence is still limited, with variability in study design, strains used, and outcome measures. Most research supports their use as part of a broader approach to mental wellness rather than as stand-alone therapy. Thus, while there is scientific validation of Bifidobacteria's potential role in stress support, the evidence is moderate and strain-specific, meriting a rating of 3 out of 5.
Other ingredients used for Stress
5-Hydroxytryptophan (5-HTP)7-Keto-DHEA
acetyl l-carnitine
alpha-pinene
arjun tree
ashwagandha
asparagus
astragalus
waterhyssop
benegut perilla (proprietary)
bergamot
bifidobacterium bifidum
bifidobacterium lactis
bifidobacterium longum
sesame
black tea
bonito peptide
bupleurum falcatum
California poppy
caterpillar mushroom
chaga mushroom
chamomile
cordyceps
curcumin
damiana
DHA (docosahexaeonic acid)
dong quai root
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
GABA (gamma aminobutyric acid)
gardenia
gotu kola
green tea
guayusa
heartwood
hibiscus
hops
jujube
kava root
kudzu
l-ornithine
l-taurine
l-theanine
l-tryptophan
l-tyrosine
lactium casein decapeptide
lactobacillus brevis
lactobacillus casei
lactobacillus helveticus
lactiplantibacillus plantarum
lavender
lentinula edodes mycelia
lion's mane
liquid liver fractions
maca
magnesium
magnolia
matcha
melatonin
mint
motherwort
muira puama
Acetyl-L-Tyrosine
oat
passionflower
peppermint oil
perilla
phosphatidylserine
phospholipids
pine bark
polygala root
pregnenolone
pyrroloquinoline disodium salt
quail egg
relora® (proprietary)
rhodiola
rose oil
saffron
sceletium
black ginger
skullcap
spearmint leaf
spinach
valerian root
velvet bean
vitamin B12
vitamin B6
mulberry
whole adrenal glandular
zinc
sarsaparilla
suma
jiaogulan
catnip
cardamom
anise
fumaria parviflora
bee pollen
lingzhi
kanna
silk tree
oriental arborvitae
anemarrhena asphodeloides
St. John's Wort
yerba mate
noni
wood betony
biota seed
goji berry
cocoa
AMP-activated protein kinase (AMPK)
ashitaba
7,8-Dihydroxyflavone
Aralia
Arjuna
akebia
Antler
Agastache
Agrimony
Apigenin
Antrodia camphorata
Arginine aspartate
Albizia
Anserina
Agmatine
Agarwood
Alpha lactalbumin
Algal protein
Betony
Baikal Skullcap
Black spruce
Baccosides
Bacopin
Baicalein
Basidiomycota
Banyan
Brahmi
Bacopa
Buddha's Hand
Borage
banana
Bifidobacteria
Bupleurum
bacoside
Baicalin
Bird's nest
Centella triterpenes
Common Monkey Flower
Clary sage
Chinese Mountain Ant
Codonopsis
Coriander
Clerodendrum phlomidis
Chinese Fleeceflower
Chuchuhuasi
Cymbopogon Martini
Calea zacatechichi
Centella asiatica
Coca
Chocolate
Capitate Valerian
Corktree
Catuaba
C-Phycocyanin
cypress
Cowslip
Calamus
Cherimoya
Convolvulus prostratus
Corydalis
Convolvulus Pluricaulis
Celastrus
Canscora
Dismutase
Dodeca-2E, 4E-Dienoic Acid Isobutylamide
Dibenzo-alpha pyrones
Devil's Club
Date
Dodeca-2E, 4E, 8Z, 10Z/Etetraenoic Acid Isobutylamide
Emblicanin
Goldthread
Glycine
jasmine
Lotus
Mistletoe
Mimosa
Orchid
Poppy
Pistachio
Rose
Spikenard
yohimbine
Other health conditions supported by Bifidobacteria
Abdominal PainAcid Indigestion
Allergies (food)
Allergies (respiratory)
Alzheimer's Disease
Antibiotics (side effects of)
Anxiety
Autoimmune Disorders
Cancer Treatment (reducing side effects)
Celiac Disease
Chemotherapy (reducing side effects)
Cholesterol (high)
Colitis
Constipation (adults)
Constipation (children)
Crohn's Disease
Diabetes
Diarrhea
Digestion (poor)
Diverticulitis
Eczema
Enteritis
Fatty Liver Disease
Gastritis
Inflammatory Bowel Disorders
Irritable Bowel Syndrome
Lactose Intolerance
Leaky Gut Syndrome
Liver Detoxification
Memory and Brain Function
Migraine
Mood Swings
Pregnancy (herbs and supplements for)
Small Intestinal Bacterial Overgrowth
Stress
Thrush
Ulcers
Vaginitis