Evidence supporting the use of: Leptospermum scoparium
For the health condition: Staph Infections
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Leptospermum scoparium (Manuka) and Staphylococcus Infections: Evidence Overview
Leptospermum scoparium, commonly known as manuka, is widely recognized for its antimicrobial properties, particularly in the form of manuka honey. The use of manuka honey for treating skin infections, including those caused by Staphylococcus aureus (including MRSA), is supported by a growing body of scientific literature.
In vitro studies have consistently demonstrated that manuka honey possesses significant bactericidal activity against Staphylococcus species. This is primarily attributed to its high methylglyoxal (MGO) content, which is unique among honeys. Several clinical studies and case reports have documented the successful use of manuka honey in wound care, showing reduced bacterial load and promotion of wound healing, even in chronic, non-healing wounds infected with resistant strains of Staphylococcus. The mechanisms of action include osmotic effects, low pH, and the presence of bioactive compounds like MGO and hydrogen peroxide.
While the bulk of high-quality evidence is limited to topical applications (such as dressings for wounds and ulcers), and not oral or systemic treatment, the scientific literature does support the use of manuka honey as an adjunctive therapy in managing superficial Staph infections. Major clinical guidelines have yet to universally endorse its use due to a lack of large-scale randomized controlled trials, but the existing data justify a moderate evidence rating.
In summary, Leptospermum scoparium (as manuka honey) is scientifically validated for topical support in Staph infection management, though more robust clinical trials are warranted to fully define its role.
More about Leptospermum scoparium
More about Staph Infections
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turmeric
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goldenseal
immunoglobin G
Japanese sophora
lactoperoxidase
lauric acid
LH01-myoviridae
LL12-myoviridae
LL5-siphoviridae
monolaurin
typhonium
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paederia foetida
smilax
pau d'arco
oriental arborvitae
camphor oil
stillingia
melaleuca alternifolia
3-Phenyllactic Acid
Alpha-terpineol
Alchornea
Aureobasidium pullulans
Andrographis
allyl isothiocyanate
Alliin
Abuta
Alantolactone
Bee Propolis
Babchi
Baphicacanthus cusia
Brazillian peppertree
Bisabolene
Brevibacillus brevis
benzyl isothiocyanate
Carvacrol
Copaiba Oil
Other health conditions supported by Leptospermum scoparium
AbrasionsAntibiotics (alternatives to)
Bites and Stings
Bleeding (external)
Blisters
Boils
Bruises (healing)
Burns and Scalds
Cuts
Dermatitis
Eye Infections
Fungal Infections
Infection
Infection (bacterial)
Inflammation
Injuries
Itching
Lesions
Rashes and Hives
Scratches and Abrasions
Skin (infections)
Skin Care (general)
Staph Infections
Sunburn
Wounds and Sores