Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Methylsulfonylmethane (MSM) is an organosulfur compound commonly marketed as a dietary supplement for joint health and inflammation. Its use for treating or supporting recovery from sprains has some scientific basis, though the evidence is limited and not robust. MSM is believed to exert anti-inflammatory and antioxidant effects, which could theoretically aid in reducing pain and swelling associated with sprains. A handful of clinical studies have examined MSM in the context of musculoskeletal injuries, though most research has focused on osteoarthritis or generalized muscle soreness rather than acute sprains specifically.

For example, a double-blind, placebo-controlled study by Kim et al. (2006) found that MSM supplementation reduced symptoms of pain and physical impairment in patients with knee osteoarthritis, possibly due to its anti-inflammatory properties. However, evidence addressing acute soft tissue injuries like sprains is sparse. Some animal studies suggest MSM might reduce swelling and promote healing after tissue injury, but these findings have not been conclusively replicated in human trials involving sprains.

Overall, MSM's use for sprains is based on its general anti-inflammatory and pain-relieving effects, yet direct clinical evidence for this specific indication is weak. Therefore, while some scientific rationale exists, the evidence supporting its use for sprains is limited and rated as low (2/5).

More about MSM (Methylsulfonylmethane)
More about Sprains

Other ingredients used for Sprains

Other health conditions supported by MSM (Methylsulfonylmethane)

Products containing MSM (Methylsulfonylmethane)