Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Triterpenes are a large class of naturally occurring compounds found in many medicinal plants, including those used in traditional Chinese medicine (TCM). In TCM, certain herbs rich in triterpenes, such as Ganoderma lucidum (Reishi mushroom) and Panax ginseng, are traditionally used to "tonify" or support the Spleen, a concept that in TCM encompasses digestion, energy production, and fluid metabolism. The rationale for their use is based on centuries of empirical herbal practice, where these botanicals are believed to strengthen the Spleen Qi, improve appetite, and combat fatigue. However, while some modern research has investigated the pharmacological activities of specific triterpenes—such as anti-inflammatory, immunomodulatory, and hepatoprotective effects—there is a lack of direct scientific studies linking triterpene use (in general or unspecified forms) to measurable improvements in human spleen function as understood in Western medicine. Most evidence remains indirect, based on traditional uses and the general bioactivity of triterpenes. Thus, the justification for using "triterpene (unspecified)" to support the Spleen body system is primarily traditional, with only limited scientific investigation and no robust clinical evidence specific to spleen support.

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