Evidence supporting the use of: Japanese sophora
For the health condition: Sore Throat

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Japanese sophora (Sophora japonica), also known as Huai Hua in traditional Chinese medicine (TCM), has a long history of use in East Asian herbalism. Its dried flower buds are commonly included in herbal formulas for conditions involving heat, bleeding, and inflammation. In traditional contexts, sore throat is often attributed to "heat" or "toxic" influences, and herbs like Japanese sophora are used to clear heat and reduce inflammation. While the primary historical application of Japanese sophora is for bleeding disorders such as hemorrhoids or bloody stool, some TCM texts and formulas include it for sore throat, especially if there is swelling or bleeding present.

Modern pharmacological studies of Sophora japonica and its main constituents, such as rutin and quercetin, have demonstrated anti-inflammatory and antioxidant effects in vitro. However, clinical trials specifically investigating its effectiveness in sore throat are lacking. Its use for sore throat remains supported mainly by traditional practice rather than robust scientific validation. Any anti-inflammatory effects present in laboratory studies have not been directly translated into clinical recommendations for sore throat.

In summary, Japanese sophora’s use for sore throat is justified by traditional herbal medicine sources, with some supportive (though indirect) evidence from modern pharmacology regarding its anti-inflammatory properties. However, the evidence base is limited and does not reach a high standard of scientific validation.

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