Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Goldthread (Coptis chinensis) has been traditionally used in Chinese medicine for the treatment of sore throat and related infections. The primary active compound in Goldthread is berberine, a well-known alkaloid with documented antimicrobial properties. Historical records from Traditional Chinese Medicine (TCM) describe the use of Goldthread as a "heat-clearing" and "detoxifying" herb, often prescribed in formulas for symptoms such as sore throat, mouth ulcers, and other inflammatory conditions of the oropharynx.

Modern research has demonstrated that berberine possesses antibacterial and anti-inflammatory effects in vitro and in animal models. Some laboratory studies suggest that Goldthread extracts can inhibit the growth of common bacteria that cause throat infections, such as Streptococcus pyogenes. However, there is a lack of well-designed human clinical trials specifically evaluating Goldthread for sore throat treatment. Most evidence remains preclinical or anecdotal, and no authoritative clinical guidelines endorse its use based on current scientific data.

In summary, the use of Goldthread for sore throat is justified primarily by traditional medical systems, backed by some preliminary pharmacological evidence, but lacks robust clinical validation.

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