Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Bisabolol, a naturally occurring sesquiterpene alcohol found primarily in German chamomile (Matricaria recutita), has a long history of use in traditional herbal medicine for soothing mucous membranes, including applications for sore throat. Traditional remedies often utilize chamomile infusions or extracts, which contain bisabolol, for their anti-inflammatory, mild analgesic, and soothing properties. Bisabolol is believed to exert its effects by reducing irritation and inflammation in the throat, potentially providing symptomatic relief. However, while there is substantial historical and ethnobotanical documentation supporting the use of chamomile (and thus bisabolol) for sore throat, direct clinical trials evaluating isolated bisabolol for this specific indication are limited. Some in vitro and animal studies have demonstrated anti-inflammatory and antimicrobial properties of bisabolol, which could theoretically benefit sore throat caused by irritation or infection, but high-quality human studies are lacking. Consequently, the use of bisabolol for sore throat is primarily justified by traditional, rather than robust scientific, evidence, and its efficacy rating is modest (2/5) due to the absence of modern clinical validation.

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