Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Desmodium species, particularly Desmodium gangeticum, have a long history of use in traditional medicine across Asia and Africa. In several cultures, these plants are used as part of herbal remedies for snake bite. Ethnobotanical studies document the use of Desmodium leaves, roots, or whole plant in decoctions or pastes, frequently in combination with other herbs, to treat symptoms of envenomation or to attempt to neutralize snake venom. The rationale is mostly based on historical practice and local healer knowledge rather than on robust scientific validation.

Some animal studies have examined extracts from Desmodium species for possible antivenom activity. For instance, in vitro experiments have reported modest inhibitory effects against certain enzymatic activities (e.g., phospholipase A2) of snake venom. However, these effects are generally weak and inconsistent, and there are no published clinical trials or strong preclinical data to confirm efficacy in humans. The bioactive compounds responsible remain largely unidentified. Thus, while the use of Desmodium for snake bite is well-established in ethnomedicine, the supporting scientific evidence is limited and not conclusive.

In summary, Desmodium is traditionally used for snake bites in some cultures, but the evidence base is largely anecdotal or preclinical, justifying a low evidence score.

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Other health conditions supported by Desmodium (unspecified)

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