Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Folinic acid (Vitamin B9), also known as leucovorin, is a biologically active form of folate. Its use in supporting the small intestine is scientifically validated primarily in the context of certain medical conditions. Folinic acid is critical for DNA synthesis and repair, cell division, and overall growth, all of which are vital processes in the rapidly dividing cells of the intestinal mucosa.

Clinical evidence supports the use of folinic acid supplementation in patients with malabsorption syndromes, such as celiac disease, Crohn’s disease, and short bowel syndrome, where the absorption of dietary folate is impaired due to damaged small intestinal lining. In these cases, folinic acid is often used because it can be absorbed and utilized even when normal folate absorption is compromised. Additionally, folinic acid is administered to prevent or treat folate deficiency induced by certain medications (e.g., methotrexate), which can cause gastrointestinal mucosal injury.

However, outside of these specific deficiencies or medical situations, there is limited direct scientific evidence that folinic acid supplementation benefits the small intestine in healthy individuals. Most research focuses on its role in preventing deficiency-related intestinal damage rather than on enhancing normal small intestinal function. Thus, while its use is strongly supported in the context of deficiency or absorption disorders, there is less evidence for generalized support of the small intestine in healthy populations.

More about Vitamin B9 (folinic acid)
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Other ingredients that support Small Intestines

2'-Fucosyllactose
Aloe vera
alpha-galactosidase
amino acids
amylase
amylopectin
asparagus
bacillus clausii
bacillus coagulans
bacillus subtilis
bayberry
berberine
Bifidobacterium bifidum
Bifidobacterium breve
Bifidobacterium infantis
Bifidobacterium lactis
Bifidobacterium longum
broccoli
rice
Brussel sprouts
butyrate triglyceride
caprylic acid
carrot
chia seed
chicory
cinnamon
coating
colostrum
turmeric
endo-peptidase
exo-peptidase
fennel
fenugreek
fiber blend (proprietary)
flavonols
flaxseed
folate
fructooligosaccharides (FOS)
fungal protease
ginger
green banana
green tea
Gymnema sylvestre
cellulose
immunoglobin G
inulin
isomalto-oligosaccharide
kale
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
L-alanyl-L-glutamine
L-glutamine
lactase
Lactobacillus acidophilus
Lactobacillus brevis
Lactobacillus bulgaricus
Lactobacillus casei
Lactobacillus fermentum
Lactobacillus gasseri
Lactobacillus helveticus
Lactobacillus paracasei
lactiplantibacillus plantarum
Lactobacillus reuteri
Lactobacillus rhamnosus
Lactobacillus salivarius
Lactococcus lactis
Lactoferrin
lemon
lipase
magnesium
Marshmallow
medium chain triglycerides (MCT)
Microbial enzymes (proprietary)
N-acetyl-glucosamine
okra
ox bile
pancreatin
parsley
pear
peptidase (DPPIV)
phellodendron amurense
phenolic compounds
phospholipids
phytase
potato starch
prebiotic blend (proprietary)
prolyl endopeptidase (PEP)
protease
protein
butyric acid
pumpkin
Saccharomyces boulardii
sardines
slippery elm bark
soybean
spinach
starch
streptococcus thermophilus
sucrase
sulforaphane glucosinolate
tributyrin
vitamin A
vitamin B
vitamin D
vitamin D3
seaweed
Water
Watermelon
xylooligosaccharides
Zinc
papaya
Pterocarpus marsupium
lingzhi
Yarrow
bile salt
sodium salt
dioscorea
electrolytes blend (proprietary)
polyphenols
trace minerals
purslane
fungal enzymes blend (proprietary)
millet seed
herbal blend (proprietary)
chickpea protein
enzymes blend (proprietary)
cayenne pepper
ashitaba
aminopeptidase
Alchornea
Alpha-glycans
Alchemilla
Agrimonia pilosa
Asteraceae
Acemannan
Algal protein
arabinoxylan
animal protein
black seed
Bifidobacterium
Bacillus indicus
Bifidobacterium adolescentis
Brassica
bran
bael
butternut
Bacillus licheniformis
bile
Bifidobacterium animalis
bee products
bitter principals
bacteria
Bifidobacteria
bile acid
Bacillus
Buckwheat
Boerhavia diffusa
bottle gourd
Centella triterpenes
curry leaf
cowpea
Cinnamomum
carvacrol
cape aloe
Citrus
cruciferous
Chitin-Glucan Complex
corktree
Clostridium butyricum
Debaryomyces hansenii
diamine oxidase
Enterococcus
egg
Eucheuma
enzyme blend
Egg protein
fig
fruit
fiber
flavonoids
fish
fatty acids
fringetree
Foxtail millet
flavones
goldthread
Glycomacropeptides
Glutamine
Glucooligosaccharides
galactosidase
Glutenase
Growth factors
glucose
galactooligosaccharides
Gymnema
Glycyrrhizin
honey
Immunoglobulin G
intrinsic factor
Konjac
Kluyveromyces lactis
kiwi
Kefir
Kluyveromyces marxianus
Lactobacillus plantarum
Lactobacillus pentosus
Lactobacillus sakei
Lactobacillus kefiranofaciens
Lactobacillus kefiri
Lactococcus rhamnosus
Legume protein
Lentil
Lactococcus casei
Lactobacillus johnsonii
lactalbumin
Lactobacillus
L. lactis
lipids
maltase
Mineral ascorbate
Mung bean
Mucilage
Millet
mannans
Monounsaturated fat
Milk Protein
Matapalo Tree
Mimosa
Mushroom
Nigella seed
Oligosaccharides
Piperine
Phyllanthus
Peptidase
polysaccharides
Pediococcus pentosaceus
Paenibacillus polymyxa
proteolytic enzymes
Propionibacterium freudenreichii
probiotics
Pediococcus acidilactici
pu-er tea
Portulaca
phaseolamin
Peptides
rockweed
Scimitar bean
Salmon Oil
Slippery Elm
Spelt
Salacia
Soy Protein
Sargassum
Terpenoids
Tagatose
Tiger Nut
Taka amylase
Yacon

Other body systems supported by Vitamin B9 (folinic acid)

Blood
Brain
Gastrointestinal Tract
Immune System
Intestinal System
Reproductive System
Small Intestines

Products containing Vitamin B9 (folinic acid)

We currently have no products on Caring Sunshine that contain this ingredient.