Evidence supporting the use of: Vitamin B9 (Folate)
For the body system: Small Intestines
Synopsis
Source of validity: Scientific
Rating (out of 5): 5
Vitamin B9 (Folate) is scientifically validated as essential for the health and function of the small intestine. Folate plays a crucial role in DNA synthesis, repair, and cellular division, which are vital processes for the rapidly dividing cells lining the intestinal mucosa. Deficiency in folate can result in villous atrophy and impaired absorption, leading to gastrointestinal symptoms such as diarrhea, weight loss, and malabsorption syndromes. Clinical studies and case reports have documented that folate deficiency can cause megaloblastic changes in the gastrointestinal tract, including the small intestine, and supplementation leads to normalization of mucosal architecture. Additionally, folate is important for the metabolism of homocysteine, and elevated homocysteine levels are associated with increased inflammation and potentially impaired gut barrier function.
Patients with malabsorptive disorders such as celiac disease, Crohn’s disease, or short bowel syndrome are at increased risk of folate deficiency due to reduced absorption in the small intestine, and supplementation is part of standard care in these populations. Multiple authoritative sources, including scientific reviews and clinical guidelines, recommend folate supplementation to prevent and treat deficiency-related complications affecting the small intestine. Therefore, the use of Vitamin B9 to support the small intestine is strongly supported by scientific evidence.
Other ingredients that support Small Intestines
2'-Fucosyllactosealoe vera
alpha-galactosidase
amino acids
amylase
amylopectin
asparagus
bacillus clausii
bacillus coagulans
bacillus subtilis
bayberry
berberine
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
broccoli
rice
brussel sprouts
butyrate triglyceride
caprylic acid
carrot
chia seed
chicory
cinnamon
coating
colostrum
turmeric
endo-peptidase
exo-peptidase
fennel
fenugreek
fiber blend (proprietary)
flavonols
flaxseed
folate
fructooligosaccharides (FOS)
fungal protease
ginger
green banana
green tea
Gymnema sylvestre
cellulose
immunoglobin G
inulin
isomalto-oligosaccharide
kale
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
l-alanyl-l-glutamine
l-glutamine
lactase
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus casei
lactobacillus fermentum
lactobacillus gasseri
lactobacillus helveticus
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
lactoferrin
lemon
lipase
magnesium
marshmallow
medium chain triglycerides (MCT)
microbial enzymes (proprietary)
n-acetyl-glucosamine
okra
ox bile
pancreatin
parsley
pear
peptidase (DPPIV)
phellodendron amurense
phenolic acids
phospholipids
phytase
potato starch
prebiotic blend (proprietary)
prolyl endopeptidase (PEP)
protease
protein
butyric acid
pumpkin
saccharomyces boulardii
sardines
slippery elm bark
soybean
spinach
starch
streptococcus thermophilus
sucrase
sulforaphane glucosinolate
tributyrin
vitamin A
vitamin B
vitamin D
vitamin D3
seaweed
water
watermelon
xylooligosaccharides
zinc
papaya
pterocarpus marsupium
lingzhi
yarrow
bile salt
sodium salt
dioscorea
electrolytes blend (proprietary)
polyphenols
trace minerals
purslane
fungal enzymes blend (proprietary)
millet seed
herbal blend (proprietary)
chickpea protein
enzymes blend (proprietary)
cayenne pepper
ashitaba
Aminopeptidase
Alchornea
Alpha-glycans
Alchemilla
Agrimonia pilosa
Asteracea
Acemannan
Algal protein
Arabinoxylan
Animal protein
Black Seed
Bifidobacterium
Bacillus indicus
Bifidobacterium adolescentis
Brassica
Bran
Bael
Butternut
Bacillus licheniformis
Bile
Bifidobacterium animalis
Bee products
Bitter principals
Bacteria
Bifidobacteria
bile acid
Bacillus
Buckwheat
Boerhavia diffusa
Bottle gourd
Centella triterpenes
Curry leaf
Cowpea
Cinnamomum
Carvacrol
Cape Aloe
Citrus
Cruciferous
Chitin-Glucan Complex
Corktree
Clostridium butyricum
Debaryomyces hansenii
Diamine Oxidase
Enterococcus
Egg
Eucheuma
Enzyme Blend
Egg protein
Fig
Fruit
Fiber
Flavonoids
Fish
Fatty acids
Fringetree
Foxtail millet
Flavones
Goldthread
Glycomacropeptides
Glutamine
Glucooligosaccharides
Galactosidase
Glutenase
glucose
Galactooligosaccharides
Glycyrrhizin
Milk Protein
Mimosa
Soy Protein
Other body systems supported by Vitamin B9 (Folate)
BloodBrain
Circulatory System
Digestive System
Female Reproductive System
Gastrointestinal Tract
Heart
Immune System
Intestinal System
Liver
Nerves
Reproductive System
Small Intestines