Evidence supporting the use of: Inulin
For the body system: Small Intestines

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Inulin is a naturally occurring soluble fiber found in many plants, such as chicory root, and is classified as a prebiotic. Scientific evidence supports its role in supporting the small intestine, primarily through its effects on gut microbiota. Inulin resists digestion in the upper gastrointestinal tract, including the small intestine, and instead is fermented by beneficial bacteria in the colon. However, some prebiotic effects may begin in the distal small intestine, where microbiota populations can utilize inulin as a substrate. Studies have shown that inulin supplementation can increase populations of beneficial bacteria, particularly bifidobacteria and lactobacilli, which in turn can improve gut barrier function and modulate immune responses. Inulin may also support the small intestine indirectly by promoting the production of short-chain fatty acids (SCFAs), such as butyrate, which have been shown to support intestinal cell health and integrity. However, most of inulin’s fermentation occurs in the colon, not the small intestine, so its direct effect on small intestine function is limited compared to its well-established benefits for overall gut health. Clinical trials generally focus on inulin’s impact on colonic health and microbiota, but some evidence suggests it may help with mineral absorption (like calcium and magnesium) in the small intestine, likely due to changes in pH and microbial metabolites. Overall, while the primary benefits of inulin are for the colon, there is moderate scientific evidence supporting its indirect support of the small intestine.

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