Enzyme blends, often containing proteases, lipases, and amylases, are used to support the small intestine's digestive function. The small intestine is the primary site for nutrient absorption, and digestive enzymes are crucial for breaking down macronutrients into absorbable units. Scientific studies have shown that supplemental digestive enzymes can aid individuals with enzyme insufficiencies—such as those with pancreatic insufficiency, cystic fibrosis, or certain gastrointestinal disorders—by improving nutrient absorption and reducing gastrointestinal symptoms like bloating and discomfort (source).

Evidence also supports the use of enzyme blends in conditions such as lactose intolerance and some forms of irritable bowel syndrome (IBS), where supplemental enzymes can assist in digesting problematic food components. However, for individuals with normal digestive function, the benefits are less pronounced, and clinical studies offer mixed results regarding the efficacy of enzyme supplementation in otherwise healthy populations.

Overall, there is solid scientific justification for using enzyme blends to support small intestine function in specific populations with digestive enzyme deficiencies. However, more research is needed for their efficacy in the general population.