Evidence supporting the use of: Bifidobacterium infantis
For the body system: Small Intestines

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Bifidobacterium infantis is a probiotic bacterium naturally found in the gut, especially in infants. There is significant scientific evidence supporting its use for supporting the small intestine and overall gut health. B. infantis is known to play a crucial role in digesting human milk oligosaccharides (HMOs), which are complex sugars present in breast milk. This digestion helps establish a healthy gut microbiome in infants, which is essential for proper development and function of the small intestine.

Clinical studies have demonstrated that supplementation with B. infantis can improve symptoms in individuals with irritable bowel syndrome (IBS), including reduced bloating and abdominal pain, both of which are linked to small intestinal function. For example, a 2006 randomized, double-blind, placebo-controlled trial published in the American Journal of Gastroenterology found that B. infantis 35624 significantly improved IBS symptoms compared to placebo. Other research has shown that B. infantis can decrease intestinal inflammation and modulate immune responses within the gut.

While most research has focused on infants and those with gastrointestinal disorders, the underlying mechanisms—such as enhancement of the intestinal barrier, competitive exclusion of pathogens, and production of beneficial short-chain fatty acids—provide a scientific rationale for its use in supporting small intestinal health in a broader population. Thus, B. infantis is scientifically justified as a probiotic for supporting small intestine function.

More about Bifidobacterium infantis
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