Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bacillus indicus is a spore-forming probiotic bacterium that has gained attention in recent years for its potential benefits in supporting gut health, including the small intestine. Scientific studies have shown that Bacillus indicus can survive the harsh conditions of the gastrointestinal tract, allowing it to reach the small intestine where it may exert beneficial effects. One of its distinguishing features is its ability to produce carotenoids, such as beta-carotene, which are antioxidants that may help reduce oxidative stress in the gut environment.

Some in vitro and animal studies suggest that Bacillus indicus can modulate the gut microbiota, enhance gut barrier function, and exhibit anti-inflammatory properties. However, direct clinical trials in humans specifically evaluating its effects on small intestine health are limited. Most of the available evidence comes from general probiotic research or from studies on multi-strain formulations, where Bacillus indicus is included alongside other Bacillus species. These studies have shown improvements in gut microbial balance and some markers of gut health, but attributing these effects solely to Bacillus indicus is challenging.

Overall, while there is moderate scientific rationale and preliminary data supporting the use of Bacillus indicus for small intestine health, the direct clinical evidence remains limited. Thus, its evidence rating is moderate (2/5), and further well-designed human studies are needed to establish its efficacy for this specific application.

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