Synopsis

Source of validity: Scientific
Rating (out of 5): 3

The Brazilian peppertree (Schinus terebinthifolia) has a history of traditional use in South American folk medicine for treating skin infections, wounds, and ulcers. In recent years, scientific studies have begun to explore its antimicrobial properties. Laboratory research has demonstrated that extracts from the leaves, bark, and berries exhibit inhibitory activity against a variety of pathogenic microorganisms, including Staphylococcus aureus, a common cause of skin infections. Notably, a 2017 study published in Scientific Reports found that a flavone-rich extract from the tree could disrupt the formation and function of S. aureus biofilms and inhibit its virulence factors, suggesting a potential role in managing skin infections where biofilm formation is a concern.

Other in vitro studies have reported antibacterial, antifungal, and even anti-inflammatory actions of Brazilian peppertree extracts. However, clinical trials in humans are lacking, and most evidence remains preclinical. Safety profiles for topical use appear favorable in limited studies, but allergic reactions have been reported. In summary, while traditional use is well established, there is moderate scientific evidence from laboratory research supporting the use of Brazilian peppertree for skin infections, warranting further clinical investigation.

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