Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin B3, also known as niacin or in its topical form as niacinamide, has scientific support for its use in improving skin health, particularly in conditions characterized by dryness and flakiness. Multiple clinical studies have demonstrated that topical niacinamide can enhance the skin barrier by increasing the synthesis of ceramides and other key lipids in the stratum corneum, the outermost layer of the skin. This improved barrier function reduces transepidermal water loss, helping the skin retain moisture and decreasing dryness and flakiness. Randomized controlled trials have shown that topical niacinamide (typically at 2-5% concentrations) can significantly improve skin hydration and reduce symptoms of xerosis (dry skin) in both healthy individuals and those with atopic dermatitis. The oral form of vitamin B3 is also essential for overall skin health, as severe deficiency (pellagra) manifests with dermatitis among other symptoms; however, for mild to moderate dryness or flakiness, topical use is more relevant and evidence-based. The mechanism involves anti-inflammatory effects as well as the upregulation of proteins and lipids that strengthen the skin barrier. Overall, the use of Vitamin B3 (especially niacinamide) for supporting or treating dry and/or flaky skin is well-supported by modern dermatological research.

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