Evidence supporting the use of: Panthenol
For the health condition: Skin (dry and/or flaky)
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Panthenol, also known as provitamin B5, is widely used in skincare products for its moisturizing and skin barrier-supporting properties. The scientific basis for its use in treating dry and/or flaky skin is well established. Panthenol is a humectant, meaning it attracts and retains moisture, which helps hydrate the skin and prevent transepidermal water loss. Multiple in vitro and in vivo studies have demonstrated that topical application of panthenol improves skin hydration, enhances skin softness, and accelerates barrier repair. For example, a 2011 review in the journal Journal of Cosmetic Science summarizes evidence showing that panthenol increases stratum corneum hydration and reduces inflammation, making it beneficial for dry and irritated skin. Clinical trials have shown that creams containing panthenol can reduce symptoms of dryness, roughness, and scaling in both healthy and compromised skin (such as in patients with atopic dermatitis or after irritant exposure). The ingredient is also well-tolerated and has a low risk of adverse reactions. Overall, the use of panthenol for dry and flaky skin is supported by a robust body of scientific evidence, although most studies are small and often use panthenol in combination with other ingredients, which is why the evidence rating is not a full 5.
Other ingredients used for Skin (dry and/or flaky)
aloe veraalpha-linolenic acid (ALA)
beeswax
biotin
borage oil
colostrum
evening primrose oil
gooseberry
linoleic acid (LA)
magnesium
omega-3 fatty acids
rehmannia glutinosa
silicon
vitamin A
vitamin E
zinc
chickweed
swertia
birch
sea salt
Alpha Hydroxy Acids
American Liverleaf
Allantoin
Acemannan
Argan nut oil
Butter
Borage
Cod Liver Oil
Cape Aloe
Cocoa Butter
Cowslip
Chestnut
Castile Soap
Emu Oil
Evening Primrose Oil
Ficus religiosa
Glycolic acid
Glyceryl oleate
Heartsease
Oak
Orchid
Spikenard
Silk protein
Other health conditions supported by Panthenol
AbrasionsBlisters
Burns and Scalds
Cuts
Dermatitis
Diaper Rash
Eczema
Lesions
Scars / Scar Tissue
Scratches and Abrasions
Skin (dry and/or flaky)
Skin Care (general)
Sunburn
Wounds and Sores