Evidence supporting the use of: Glycolic acid
For the health condition: Skin (dry and/or flaky)
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Glycolic acid, an alpha-hydroxy acid (AHA) derived from sugar cane, is widely used in dermatology and skincare for its exfoliating properties. Scientific studies support its use for treating dry and flaky skin primarily due to its keratolytic effect, which helps to remove the outermost layer of dead skin cells (stratum corneum). By promoting exfoliation, glycolic acid enhances skin cell turnover and allows healthier, more hydrated skin cells to surface. This process can result in smoother, softer skin and improved moisture retention.
Clinical research demonstrates that topical application of glycolic acid (in concentrations ranging from 5% to 20%) can significantly improve skin texture, hydration, and the appearance of xerosis (dry, rough skin). For example, a randomized controlled trial published in Dermatologic Surgery (2002) found that glycolic acid-containing creams improved dry and rough skin over several weeks of use. Additionally, glycolic acid facilitates penetration of moisturizers and other active ingredients, further supporting its use in managing dry or flaky skin.
While glycolic acid is generally effective, it can cause irritation or increased sensitivity, especially in those with very sensitive or compromised skin barriers. Thus, its use should be tailored to individual tolerance levels. In summary, the scientific literature provides a solid basis for the use of glycolic acid in addressing dry and flaky skin, with moderate to strong evidence supporting its efficacy.
Other ingredients used for Skin (dry and/or flaky)
Aloe veraalpha-linolenic acid (ALA)
beeswax
biotin
borage oil
colostrum
evening primrose oil
gooseberry
linoleic acid (LA)
magnesium
omega-3 fatty acids
rehmannia glutinosa
silicon
vitamin A
vitamin E
Zinc
chickweed
Swertia
birch
sea salt
Alpha hydroxy acids
American Liverleaf
Allantoin
Acemannan
argan nut oil
butter
borage
cod liver oil
cape aloe
cocoa butter
cowslip
chestnut
castile soap
emu oil
evening primrose oil
fat liver oil
Ficus religiosa
Glycolic acid
glyceryl oleate
Heartsease
Lilium polyphyllum
linseed oil
Mucilage
Milkweed
Oak
orchid
Phlebodium decumanum
Panthenol
Rubus
rockweed
Spikenard
Silk protein
Sulfur
Sargassum
Servicetree
Witch Hazel
Other health conditions supported by Glycolic acid
AcneAge Spots
Canker Sores
Dandruff
Gingivitis
Lesions
Psoriasis
Scars / Scar Tissue
Seborrhea
Skin (dry and/or flaky)
Skin (oily)
Skin Care (general)
Warts
Wounds and Sores
Wrinkles