Borage (Borago officinalis) is primarily valued for its seeds, which are a rich source of gamma-linolenic acid (GLA), an omega-6 fatty acid. GLA is an essential fatty acid that plays a role in maintaining healthy skin barrier function and hydration. Several clinical studies have investigated the effects of borage oil supplementation on skin conditions characterized by dryness and flakiness, such as atopic dermatitis and eczema. Some randomized controlled trials have demonstrated that borage oil can improve skin hydration and reduce transepidermal water loss, likely due to the restoration of the skin’s lipid barrier by GLA. However, other studies have shown mixed or minimal effects, leading to some controversy about its efficacy.

Overall, there is moderate scientific support for the use of borage oil in managing dry or flaky skin, particularly in populations with underlying fatty acid deficiencies. The evidence is stronger for oral supplementation than for topical application. Safety is generally good, but some products may contain hepatotoxic pyrrolizidine alkaloids if not properly processed. In summary, borage oil’s use for dry or flaky skin is supported by scientific evidence, but results are not uniformly positive and further research is warranted.