Evidence supporting the use of: Vitamin A
For the health condition: Skin Care (general)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin A is scientifically validated for its role in general skin care. Vitamin A encompasses a group of compounds including retinol, retinal, and retinoic acid, which are essential for maintaining healthy skin. Retinoids (synthetic and natural derivatives of vitamin A) are widely used in both over-the-counter and prescription skin care products. Their mechanisms of action include promoting cell turnover, stimulating collagen production, and regulating sebum (oil) production, all of which contribute to improved skin texture and appearance.

Numerous clinical studies demonstrate that topical retinoids can reduce the appearance of fine lines, wrinkles, and hyperpigmentation, and are effective in treating acne. Oral vitamin A supplementation is also crucial for preventing and treating xerosis (dry, rough skin) and other symptoms of deficiency. However, oral supplementation is typically reserved for those with a diagnosed deficiency due to potential toxicity at high doses.

The dermatological benefits of vitamin A have been recognized since the 20th century, and its derivatives remain gold-standard treatments in dermatology for both cosmetic and medical indications. However, its use should be monitored due to potential irritation, photosensitivity, and, with oral forms, systemic toxicity. In summary, the use of vitamin A in supporting general skin health is strongly supported by scientific evidence, particularly when used in topical formulations.

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