Evidence supporting the use of: Tyrosinase
For the health condition: Skin Care (general)
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Tyrosinase is a copper-containing enzyme that plays a critical role in the production of melanin, the pigment responsible for skin color. In skin care, tyrosinase is not used to support skin health directly, but rather, it is a key target for inhibition in order to manage hyperpigmentation and related concerns. Many skin care products contain tyrosinase inhibitors (such as kojic acid, arbutin, and hydroquinone), which work by blocking the activity of tyrosinase, thereby reducing melanin synthesis and leading to a lightening effect on the skin. The scientific rationale for targeting tyrosinase in cosmetic and dermatological products is well established, with numerous studies demonstrating the efficacy of tyrosinase inhibitors for reducing hyperpigmentation and improving overall skin tone. However, the enzyme itself is not typically added to skin care products; rather, its activity is modulated. In summary, the use of tyrosinase as a target in skin care formulations is strongly supported by scientific evidence, specifically for the treatment of conditions involving unwanted pigmentation, such as melasma, age spots, and post-inflammatory hyperpigmentation.
Other ingredients used for Skin Care (general)
aloe veraanthocyanins
apple
apricot
astaxanthin
beeswax
beet
beta-carotene
black currant
radish
sesame
bovine gelatin
catalase
colostrum
cryptoxanthin
cucumber
d-alpha tocopherol
dog rose
heartwood
hyaluronic acid
l-cysteine
l-glutathione
l-histidine
linoleic acid (LA)
lovage
lychee
magnesium
mango
mixed carotenoids
oat
omega-3 fatty acids
pumpkin
redcurrant
silicon
keratin
spinach
starch
tomato
almond fruit
Urolithin A
vitamin A
vitamin C
vitamin E
watercress
watermelon
zinc
sarsaparilla
red clover
chickweed
oryza
root tuber
birch
dulse leaf
camphor oil
goji berry
amaranth
sea salt
3,3'-dihydroxy-B-carotene-4,4'-dione
Alpha-terpineol
Azelaic acid
Arbutin
Avocado
Anserina
Ascophyllum nodosum
Alpha Hydroxy Acids
Asam gelugor
Allantoin
anthocyanidins
Algal protein
Argan nut oil
Abalone
Behenic Acid
Biopeptide
Black spruce
beta-zeacarotene
Brassica
Bisabolene
Butternut
Borage
Bottle gourd
Bird's nest
California chia
Chervil
Carnosine
Candelilla wax
Cocoa Butter
Cereal grass
Citral
Castile Soap
Copaiba Oil
Currant
Dunaliella salina
David's Milkberry
Dulse
Egg
Emu Oil
Flavans
Geraniol
Glycolic acid
Glyceryl oleate
Gac
Glucosylceramide
Glycosylceramides
Heartsease
Himalayan Salt
Oak
Orchid
Rose
Snakeroot (unspecified)
Silk protein
silica
vegetable oil