Evidence supporting the use of: Proanthocyanidin (unspecified)
For the health condition: Skin Care (general)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Proanthocyanidins are a class of polyphenolic compounds found in many plants, notably in grape seeds, pine bark, and certain berries. Their use in general skin care is supported primarily by their antioxidant properties, which have been explored in several laboratory and small clinical studies. In vitro and animal studies suggest that proanthocyanidins can protect skin cells from oxidative stress induced by UV radiation and pollution, potentially reducing the signs of aging and supporting skin health. Some human studies, though generally small in scale, have shown that oral supplementation with proanthocyanidins (especially from grape seed extract or pine bark extract) may improve skin elasticity, hydration, and reduce hyperpigmentation. For example, a few randomized controlled trials have reported modest improvements in skin appearance and reduction in melasma with proanthocyanidin supplementation. However, comprehensive clinical evidence is lacking; most studies have limitations such as small sample sizes, short duration, or lack of replication. There is also some evidence from traditional use, but the scientific rationale predominates in modern skin care formulations. Overall, while there is scientific basis for the inclusion of proanthocyanidins in skin care, the strength of evidence is moderate at best (score: 2), and more robust, large-scale clinical trials are needed to confirm efficacy and optimal usage.

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Products containing Proanthocyanidin (unspecified)

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