Evidence supporting the use of: Phytoene
For the health condition: Skin Care (general)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Phytoene is a colorless carotenoid found naturally in various fruits and vegetables and is a precursor in the biosynthetic pathway of other carotenoids. Its use in skin care has emerged primarily due to its antioxidant properties. Several laboratory and preclinical studies suggest that phytoene, along with its derivative phytofluene, can help protect skin cells from oxidative stress induced by ultraviolet (UV) light and environmental pollutants. These antioxidative effects may contribute to the prevention of photoaging and the maintenance of skin health. Additionally, some small clinical studies and in vitro experiments have indicated that phytoene can reduce UV-induced erythema (skin redness) and may support an even skin tone by modulating melanin production and inflammatory responses in skin cells.
However, while the experimental and mechanistic evidence is promising, robust clinical trials in humans are currently limited. Most available data come from studies on carotenoid-rich extracts, rather than isolated phytoene, making it difficult to attribute observed effects solely to this compound. As such, the evidence supporting phytoene’s specific benefits in general skin care is moderate and mostly based on its antioxidant potential rather than direct clinical outcomes. Further research is needed to confirm its efficacy and optimal usage in dermatological applications.
Other ingredients used for Skin Care (general)
aloe veraanthocyanins
apple
apricot
astaxanthin
beeswax
beet
beta-carotene
black currant
radish
sesame
bovine gelatin
catalase
colostrum
cryptoxanthin
cucumber
d-alpha tocopherol
dog rose
heartwood
hyaluronic acid
l-cysteine
l-glutathione
l-histidine
linoleic acid (LA)
lovage
lychee
magnesium
mango
mixed carotenoids
oat
omega-3 fatty acids
pumpkin
redcurrant
silicon
keratin
spinach
starch
tomato
almond fruit
Urolithin A
vitamin A
vitamin C
vitamin E
watercress
watermelon
zinc
sarsaparilla
red clover
chickweed
oryza
root tuber
birch
dulse leaf
camphor oil
goji berry
amaranth
sea salt
3,3'-dihydroxy-B-carotene-4,4'-dione
Alpha-terpineol
Azelaic acid
Arbutin
Avocado
Anserina
Ascophyllum nodosum
Alpha Hydroxy Acids
Asam gelugor
Allantoin
anthocyanidins
Algal protein
Argan nut oil
Abalone
Behenic Acid
Biopeptide
Black spruce
beta-zeacarotene
Brassica
Bisabolene
Butternut
Borage
Bottle gourd
Bird's nest
California chia
Chervil
Carnosine
Candelilla wax
Cocoa Butter
Cereal grass
Citral
Castile Soap
Copaiba Oil
Currant
Dunaliella salina
David's Milkberry
Dulse
Egg
Emu Oil
Flavans
Geraniol
Glycolic acid
Glyceryl oleate
Gac
Glucosylceramide
Glycosylceramides
Himalayan Salt
Oak
Orchid
Rose
Snakeroot (unspecified)
Silk protein
silica
vegetable oil
Other health conditions supported by Phytoene
Aging (prevention)Free Radical Damage
Inflammation
Skin Care (general)
Wrinkles