Vitamin K is scientifically validated as an essential nutrient for bone health and the skeletal system. Its primary role involves the activation of proteins required for bone mineralization, particularly osteocalcin, which is crucial for binding calcium to the bone matrix. Without sufficient vitamin K, osteocalcin remains inactive, leading to impaired bone mineralization and increased risk of fractures.

There are two main forms of vitamin K relevant to bone health: vitamin K1 (phylloquinone) and vitamin K2 (menaquinones). Several observational studies and randomized controlled trials have shown an association between higher intake or supplementation of vitamin K and improved bone mineral density, as well as reduced fracture risk, particularly in older adults. Notably, a 2006 meta-analysis in the journal Archives of Internal Medicine found that vitamin K2 supplementation significantly reduced the risk of vertebral and hip fractures.

Moreover, the European Food Safety Authority (EFSA) and other regulatory bodies recognize vitamin K’s role in the maintenance of normal bones. While vitamin K is not used as a standalone treatment for osteoporosis, it is widely accepted as a supportive nutrient for skeletal health, especially when combined with other bone-supportive nutrients like calcium and vitamin D.

In summary, the use of vitamin K to support the skeletal system is strongly supported by scientific evidence, particularly regarding its critical role in bone metabolism and fracture prevention.