Evidence supporting the use of: Vitamin D (ergocalciferol)
For the body system: Skeletal System (Bones)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin D, including its form ergocalciferol (vitamin D2), is scientifically validated for its role in supporting the skeletal system. Vitamin D is essential for the regulation of calcium and phosphorus metabolism, which are critical minerals for bone health. It enhances intestinal absorption of calcium, facilitating the mineralization of bone. Deficiency in vitamin D leads to impaired bone mineralization, resulting in conditions such as rickets in children and osteomalacia in adults. Numerous clinical studies and meta-analyses confirm that vitamin D supplementation reduces the risk of fractures and improves bone mineral density, especially when combined with calcium. Guidelines from organizations such as the Institute of Medicine and the Endocrine Society recommend vitamin D supplementation for populations at risk of deficiency to support bone health and prevent osteoporosis. Ergocalciferol, while slightly less potent than cholecalciferol (vitamin D3), is still effective in raising serum 25-hydroxyvitamin D levels and is used therapeutically, particularly in patients with dietary restrictions. Thus, the use of vitamin D (ergocalciferol) for skeletal system support is strongly grounded in scientific evidence.

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