Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Strontium, particularly in the form of strontium ranelate, has been studied for its effects on bone health and the prevention of osteoporosis. Scientific evidence indicates that strontium can positively influence bone metabolism: it both stimulates bone formation by osteoblasts and reduces bone resorption by osteoclasts. Several clinical trials, most notably the SOTI and TROPOS studies, have shown that strontium ranelate can reduce the risk of vertebral and, to a lesser extent, non-vertebral fractures in postmenopausal women with osteoporosis. These results led to its approval for the treatment of osteoporosis in some countries. However, strontium is not a standard dietary supplement for bone health, and its use is limited by concerns over potential cardiovascular risks, such as increased risk of heart attack and blood clots. Regulatory authorities like the European Medicines Agency have restricted its use to patients who cannot use other osteoporosis treatments. Strontium is not recommended as a substitute for calcium or vitamin D in bone health, and its over-the-counter forms (e.g., strontium citrate) lack the clinical evidence supporting the prescription drug. In summary, there is moderate scientific evidence supporting the use of certain forms of strontium for bone health, but its use is limited due to safety concerns and is not universally recommended for general skeletal support.

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