Evidence supporting the use of: Rhemannia
For the body system: Skeletal System (Bones)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Rehmannia (Rehmannia glutinosa) is a traditional Chinese medicinal herb historically used to support various body systems, including the skeletal system. Its use in bone health is primarily rooted in traditional Chinese medicine (TCM), where it is often included in formulas designed to "nourish the kidney." In TCM theory, the kidneys are believed to govern the bones, and Rehmannia is thought to replenish kidney essence (jing), which in turn supports bone strength and health. Classic formulas such as Liu Wei Di Huang Wan, which contains Rehmannia, are historically prescribed to address symptoms like weak bones, lower back pain, and joint issues associated with kidney deficiency.

Modern scientific research on Rehmannia's direct effects on the skeletal system is limited and largely preliminary. Some animal studies suggest that Rehmannia extracts may influence bone metabolism, possibly by modulating osteoblast (bone-forming cell) activity and reducing bone loss in models of osteoporosis. However, clinical evidence in humans is lacking, and no robust, large-scale trials have confirmed its efficacy for bone health. Thus, while Rehmannia's use for the skeletal system is well-established in traditional practice, scientific validation remains modest at best.

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