Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Fish peptides, particularly those derived from collagen, have garnered scientific interest for their potential benefits to the skeletal system. These peptides are short chains of amino acids obtained through the enzymatic hydrolysis of fish collagen, a major structural protein found in bone and connective tissue. Several studies, primarily in animal models and some in humans, have indicated that collagen peptides may stimulate osteoblast (bone-forming cell) activity, enhance bone mineral density, and inhibit bone resorption. For example, research published in journals such as Osteoporosis International and Journal of Medicinal Food has demonstrated that supplementation with fish collagen peptides can improve bone microarchitecture and biomechanical strength, particularly in models of osteoporosis. The mechanism is thought to involve the upregulation of genes related to bone formation and the improvement of calcium absorption. However, while the results are promising, most clinical evidence is preliminary, with relatively small sample sizes and varying peptide preparations. There is a need for more robust, large-scale human trials to confirm the efficacy and optimal dosing of fish peptides for bone health. Nevertheless, based on current scientific literature, there is a reasonable basis for their use in supporting the skeletal system, especially when derived from collagen-rich fish sources.

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