Evidence supporting the use of: Epimedium extract
For the body system: Skeletal System (Bones)
Synopsis
Source of validity: Traditional
Rating (out of 5): 3
Epimedium extract, commonly known as "Horny Goat Weed," has a long history of use in traditional Chinese medicine (TCM) for supporting bone health and treating conditions such as osteoporosis. In TCM, Epimedium is believed to tonify the kidney and liver, which are considered crucial for maintaining strong bones according to traditional theory. Ancient texts and modern herbal formularies frequently recommend Epimedium for the elderly or those with weakened skeletal systems.
Some modern scientific studies have investigated the effects of Epimedium, particularly its active compound icariin, on bone metabolism in animal models. These studies suggest that icariin may stimulate osteoblast activity (cells responsible for bone formation), inhibit osteoclasts (cells involved in bone resorption), and potentially help prevent bone loss. However, robust clinical evidence in humans is lacking, and most positive results are preclinical or from small-scale trials. Therefore, while traditional use is strong and some scientific rationale exists, the evidence base is not yet sufficient for a high scientific rating.
In summary, Epimedium extract’s use for skeletal support is primarily justified by traditional use, with limited but promising preclinical scientific support. More high-quality human studies are necessary to confirm effectiveness and safety for bone health.
More about Epimedium extract
More about Skeletal System (Bones)
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alfalfaalpha-ketoglutarate (AKG)
amino acids
sesame
boron
Indian frankincense
bovine
bovine gelatin
broccoli
calcium
cartilage
Chinese salvia root
chondroitin
cissus quadrangularis
collagen
collard
devil's claw
fish protein
gelatin
genistein
genistin
green lipped mussel
horsetail
ipriflavone
magnesium
manganese
microcrystalline hydroxyapatite concentrate (MCHC)
milk
phosphorus
protein
prune
rehmannia glutinosa
sardines
silicon
spinach
strontium
vitamin C
vitamin D
vitamin D3
vitamin K
seaweed
water
boneset
solomon's seal
eucommia
trace minerals
herbal blend (proprietary)
algae
soy isoflavones
Arugula
Antler
Achyranthes
Algas calcareas
Animal protein
Boswellic Acid
Beef
Bone Marrow
Baicalein
Bovine Protein
Borate
Boswellia
Bone Protein
bovine cartilage / glycosaminoglycan
Buckwheat
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Chinese Silkvine
Chinese Mountain Ant
Citrate malate
Cod Liver Oil
Chinese Pond Turtle
Chuchuhuasi
Cruciferous
Corallina officinalis
Dolomite
Daidzein
Deer Velvet
Drynaria
Dipsacus
Egg
Elk antler
Glycosaminoglycans
Isoflavones
Molasses
Milk Protein
Phosphate Salt
Soy Protein
Other body systems supported by Epimedium extract
BloodCirculatory System
Female Reproductive System
Immune System
Kidneys
Male Reproductive System
Muscles
Reproductive System
Skeletal System (Bones)
Testosterone