Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Citrate malate, more specifically as "calcium citrate malate" (CCM), is scientifically validated for its role in supporting the skeletal system, particularly bone health. CCM is a compound of calcium with citric acid and malic acid, designed to enhance calcium absorption. Multiple clinical studies have demonstrated that CCM has superior bioavailability compared to other common calcium salts, such as calcium carbonate. This means that more calcium is absorbed from CCM, which is crucial for maintaining bone mineral density and preventing osteoporosis, especially in at-risk populations like postmenopausal women and the elderly.

A 1990 study published in the "American Journal of Clinical Nutrition" found that CCM supplementation significantly improved bone mass in children and adolescents. Further, a 2007 meta-analysis in "Osteoporosis International" concluded that calcium citrate malate supplementation contributes to higher bone mineral density and reduces fracture risk. The mechanism underlying this effect is the provision of bioavailable calcium, a key mineral for the formation and maintenance of bone matrix.

While traditional use is less documented, the scientific consensus supports the use of CCM in dietary supplements aimed at bone health. Its favorable absorption profile and positive clinical outcomes make it a recommended source of supplemental calcium for skeletal system support.

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