Evidence supporting the use of: Amino acids
For the body system: Skeletal System (Bones)
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Amino acids are scientifically validated as important contributors to the health and maintenance of the skeletal system. Collagen, the most abundant protein in bone, is composed of amino acids—mainly glycine, proline, and hydroxyproline—and provides the structural matrix for bone mineralization. Several studies have shown that adequate dietary intake of essential amino acids supports bone formation and maintenance. For example, research published in journals such as "Osteoporosis International" and "The Journal of Nutrition" demonstrates that protein malnutrition is associated with decreased bone mass and increased fracture risk, especially in the elderly.
Specific amino acids, such as lysine and arginine, have been shown to enhance calcium absorption and stimulate the production of bone growth factors. Furthermore, amino acids are required for the synthesis of non-collagenous proteins involved in bone structure and function. Clinical trials have indicated that supplementation with amino acids or collagen hydrolysates may improve bone mineral density and reduce bone loss, although the effect size varies and is often more pronounced in populations at risk for osteoporosis.
In summary, there is substantial scientific evidence supporting the role of amino acids in bone health, not only as building blocks for bone proteins but also as modulators of bone metabolism and calcium utilization. Nevertheless, they should be viewed as part of an overall balanced diet, as protein excess or deficiency can both negatively impact skeletal health.
Other ingredients that support Skeletal System (Bones)
alfalfaalpha-ketoglutarate (AKG)
amino acids
sesame
boron
Indian frankincense
bovine
bovine gelatin
broccoli
calcium
cartilage
Chinese salvia root
chondroitin
cissus quadrangularis
collagen
collard
devil's claw
fish protein
gelatin
genistein
genistin
green lipped mussel
horsetail
ipriflavone
magnesium
manganese
microcrystalline hydroxyapatite concentrate (MCHC)
milk
phosphorus
protein
prune
rehmannia glutinosa
sardines
silicon
spinach
strontium
vitamin C
vitamin D
vitamin D3
vitamin K
seaweed
water
boneset
solomon's seal
eucommia
trace minerals
herbal blend (proprietary)
algae
soy isoflavones
Arugula
Antler
Achyranthes
Algas calcareas
Animal protein
Boswellic Acid
Beef
Bone Marrow
Baicalein
Bovine Protein
Borate
Boswellia
Bone Protein
bovine cartilage / glycosaminoglycan
Buckwheat
Comfrey
Chinese Silkvine
Chinese Mountain Ant
Citrate malate
Cod Liver Oil
Chinese Pond Turtle
Chuchuhuasi
Cruciferous
Corallina officinalis
Dolomite
Daidzein
Deer Velvet
Drynaria
Dipsacus
Egg
Elk antler
Glycosaminoglycans
Isoflavones
Molasses
Milk Protein
Phosphate Salt
Soy Protein
Other body systems supported by amino acids
ArteriesBlood
Brain
Circulatory System
Cortisol
Digestive System
Dopamine
Female Reproductive System
GABA
Gastrointestinal Tract
Glandular System
Hair
Heart
Hepatic System
Hypothalamus
Immune System
Intestinal System
Joints
Kidneys
Liver
Male Reproductive System
Mitochondria
Muscles
Nails
Nerves
Ovaries
Pituitary
Reproductive System
Serotonin
Skeletal System (Bones)
Skin
Small Intestines
Stomach
Testes
Thymus
Thyroid Gland