Evidence supporting the use of: Achyranthes bidentata
For the body system: Skeletal System (Bones)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Achyranthes bidentata, known as "Niuxi" in traditional Chinese medicine (TCM), has a long history of use for supporting the skeletal system, particularly in strengthening bones and joints. According to classical TCM texts and centuries of clinical practice, Achyranthes bidentata is included in formulas to "tonify the liver and kidneys," which are believed to govern bone health, and to "invigorate blood" and "strengthen sinews and bones." It is commonly prescribed for conditions such as lower back pain, weakness in the knees, joint pain, and in some cases, to aid recovery from fractures. Modern pharmacological research provides some support for these traditional uses. Preliminary animal studies and in vitro research suggest that extracts of Achyranthes bidentata may promote osteoblast (bone-forming cell) proliferation, enhance bone mineral density, and modulate bone metabolism markers. Some compounds in the herb, such as saponins, have demonstrated anti-inflammatory and antioxidant effects, which may play a role in protecting bone and joint tissues. However, robust clinical trials in humans are limited, and most evidence comes from traditional use and preclinical studies rather than large-scale, high-quality human research. In summary, the use of Achyranthes bidentata to support the skeletal system is primarily justified by traditional medicine, with some emerging scientific data offering plausible mechanisms, but definitive clinical validation is still lacking.

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