Evidence supporting the use of: Quercetin
For the body system: Sinuses

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Quercetin is a flavonoid found in many fruits and vegetables, and it has been investigated for its potential benefits in supporting sinus health, primarily due to its anti-inflammatory and antioxidant properties. Scientific studies suggest that quercetin can inhibit the release of histamine from immune cells, which may help reduce symptoms associated with allergic rhinitis—a common contributor to sinus discomfort. Some in vitro and animal studies have demonstrated that quercetin can decrease inflammation and oxidative stress in the respiratory tract. However, human clinical trials specifically focusing on quercetin’s effects on sinus health are limited, and the available studies are often small or have methodological weaknesses.

Most of the evidence supporting quercetin for sinus health is extrapolated from its broader effects on allergy symptoms and inflammation. For example, a few small clinical trials have shown that quercetin supplementation can reduce symptoms of allergic rhinitis, such as nasal congestion and runny nose, which are closely related to sinus issues. Despite these promising findings, larger and more rigorous human studies are needed to confirm its effectiveness specifically for sinus support.

In summary, while there is some scientific evidence suggesting quercetin may help support the sinuses via its anti-inflammatory and antihistamine effects, the strength of this evidence is moderate at best, warranting a rating of 2 out of 5.

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