Evidence supporting the use of: Pungent compounds (unspecified)
For the body system: Sinuses

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Pungent compounds—such as those found in horseradish, wasabi, mustard, garlic, and onions—have a long history of traditional use to support sinus health. In various folk medicine systems, these ingredients are used to help relieve nasal congestion and promote sinus drainage. The mechanism is thought to involve the irritation of mucous membranes, which stimulates increased secretion and may help to clear blocked nasal passages. For example, allyl isothiocyanate from mustard and horseradish is known to cause a burning sensation in the nose and eyes, often leading to a reflex increase in mucus production. Garlic (Allium sativum) and onions contain sulfur compounds that are also associated with these effects. While there is widespread anecdotal and traditional support for the use of pungent compounds for sinus relief, scientific studies specifically validating their efficacy for sinus or respiratory system support are limited. Most available evidence is either mechanistic (explaining how these compounds might work) or anecdotal, rather than being based on rigorous clinical trials. Therefore, the justification for their use is primarily traditional, supported by plausible mechanisms but lacking strong scientific validation.

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